Nobil Bio Ricerche has acquired the ISO9001 and ISO13485 qualification for the design and production od biomimetic materials for medical devices. It has a developing program for innovative materials for bone regeneration, inspired by the studies carried out of surface modifications and the interaction between materials and cells. The first product of this business, Synergoss, synthetic granular filler with a surface collagen cover, has received the CE mark on 2013, while come other products are still in the process of certification and development.